Grégory Chagnon Homepage.

About Me

My works focus on the mechanical behaviour of materials in large deformations and concern principally soft tissues, bioresorbable polymers and rubber-like materials. A main part of my work aims at creating architectured materials that can endure large anisotropic deformations. This work lays on experimental and computational solid mechanics and mechanical engineering studies.

Positions

  • 2013 - now - Associate Professor University of Grenoble, Laboratory TIMC-IMAG
  • 2004 - 2013 - Associate Professor University of Grenoble, Laboratory 3SR
  • 2003 - 2004 - Assistant Professor IFMA Clermont-Ferrand
  • Degrees

  • 2011 - Habilitation Thesis - University of Grenoble
  • 2003 - PhD Thesis - Ecole Centrale of Nantes
  • 2000 - MS Mechanics of Materials - Ecole Centrale of Nantes
  • Research Interests

  • Biomechanics;
  • Soft tissues;
  • Rubber-like materials (Silicone rubber);
  • Bioelastomers mechanics for medical application;
  • Architectured materials;
  • Publications

    For my citation indices, see Google Scholar or ResearcherId

    For my Research Gate profile

    Thesis

    [3] Chagnon Grégory
    Contribution to the study of architectured materials in large deformations for biomedical applications
    Habilitation thesis, University of Grenoble, France (2011).

    [2] Chagnon Grégory
    Modelling of Mullins effect in rubber like materials
    PhD thesis, Ecole Centrale de Nantes, France (2003).

    [1] Chagnon Grégory
    Modelling of damage in rubber like materials
    Master thesis, Ecole Centrale de Nantes, France (2000).

    Articles in peer-reviewed journals

    [44] Alonso, T., Chagnon, G., Favier, D. (2019).
    Characterizing transformation phenomena and elastic moduli of austenite and oriented martensite of superelastic Thin NiTi wire through isothermal dynamic mechanical analysis.
    Journal of Materials Engineering and Performance, in press. doi link and HAL

    [43] Girard, E., Chagnon, G., Gremen, E., Calvez, M., Masri, C., Boutonnat, J., Trilling, B., Nottelet, B. (2019).
    Biomechanical behaviour of human bile duct wall and impact of cadaveric preservation processes.
    Journal of the Mechanical Behavior of Biomedical Materials, 98, 291-300. doi link and HAL

    [42] Schaefer, P.L., Chagnon, G., Moreau-Gaudry, A. (2019).
    Strain Gauges Based 3D Shape Monitoring of Beam Structures Using Finite Width Gauge Model .
    Experimental Techniques, 57, 1901-1916. doi link and HAL

    [41] Tan, C.J., Lee, J.L.L., Bee Chin, A., Andriyana, A., Chin, A.B., Chagnon, G., Sukiman, M. S. (2019).
    Design of Polyurethane Fibers: Relation between theSpinning Technique and the Resulting Fiber Topology.
    Journal of Applied Polymer Science, 136, 47706 doi link and HAL

    [40] Schaefer, P.L., Barrier, G., Chagnon, G., Alonso, T., Moreau-Gaudry, A. (2019).
    Strain Gauges Based 3D Shape Monitoring of Beam Structures Using Finite Width Gauge Model .
    Experimental Techniques doi link and HAL

    [39] Elahi, S.A., Connesson, N., Chagnon, G., Payan, Y. (2019).
    In-Vivo Soft Tissues Mechanical Characterization: Volume-Based Aspiration Method Validated on Silicones.
    Experimental Mechanics, 59(251) doi link and HAL

    [38] Tan, C.J., Andriyana, A., Chin, A.B., Chagnon, G. (2018).
    Inelastic deformation of highly aligned dry-spun thermoplastic polyurethane elastomer microfibres.
    Materials Research Express, 5 (12), 125301 doi link and HAL

    [37] Dalla Monta, A., Razan, F., Le Cam, J.B., Chagnon, G. (2018).
    Using thickness-shear mode quartz resonator for characterizing the viscoelastic properties of PDMS during cross-linking, from the liquid to the solid state and at different temperatures.
    Sensors and Actuators, A Physical, 280, 107-113 doi link and HAL

    [36] Masri, C., Chagnon, G., Favier, D., Sartelet, H., Girard, E. (2018).
    Experimental characterization and constitutive modeling of the biomechanical behavior of male human urethral tissues validated by histological observations.
    Biomechanics and Modeling in mechanobiology, 17, 939 doi link and HAL

    [35] Masri, C., Chagnon, G., Favier, D. (2017).
    Influence of processing parameters on the macroscopic mechanical behavior of PVA hydrogels.
    Materials Science and Engineering C, 75, 769-776 doi link and HAL

    [34] Machado, G., Stricher, A., Chagnon, G., Favier, D. (2017).
    Mechanical behavior of architectured photosensitive silicone membranes: experimental data and numerical analysis.
    Mechanics of Advanced Materials and Structures, 24, 524-533 doi link and HAL

    [33] Rebouah, M., Chagnon, G., Heuillet, P. (2017).
    Anisotropic viscoelastic models in large deformation for architectured membranes.
    Mechanics of Time-Dependent Materials, 21(2), 163-176. doi link and HAL

    [32] Breche, Q., Chagnon, G., Machado, G., Nottelet, B., Garric, X., Girard, E., Favier, D. (2016).
    A non-linear viscoelastic model to describe the mechanical behavior's evolution of biodegradable polymers during hydrolytic degradation.
    Polymer Degradation and Stability, 131, 145-156. doi link and HAL

    [31] Stricher, A., Rinaldi, R. G., Machado, G., Chagnon, G., Favier, D., Chazeau L., Ganachaud, F. (2016).
    Light-Induced Bulk Architecturation of PDMS Membranes.
    Macromolecular Materials and Engineering, 301, 1151-1157 doi link and HAL

    [30] Marckmann, G., Chagnon, G., Le Saux, M., Charrier, P. (2016).
    Experimental investigation and theoretical modelling of induced anisotropy during stress-softening of rubber.
    International Journal of Solids and Structures, 97-98, 554-565. doi link and HAL

    [29] Breche, Q., Chagnon, G., Machado, G., Girard, E., Nottelet, B., Garric, X., Favier, D. (2016).
    Mechanical behaviour's evolution of a PLA-b-PEG-b-PLA triblock copolymer during hydrolytic degradation.
    Journal of the Mechanical Behavior of Biomedical Materials, 60, 288-300. doi link and HAL

    [28] Samuel, R., Girard, E., Chagnon, G., Dejean, S., Favier, D., Coudane, J., Nottelet, B. (2015).
    Radiopaque Poly(ε-caprolactone) as Additive for X-Ray Imaging of Temporary Implantable Medical Devices.
    Royal Society of Chemistry Advances, 5, 84125. doi link and HAL

    [27] Delobelle, V., Chagnon, G., Favier, D., Alonso, T. (2015).
    Study of electropulse heat treatment of cold worked NiTi wire: from uniform to localised tensile behaviour.
    Journal of Materials Processing Technology, 227, 244-250. doi link and HAL

    [26] Andriyana, A., Loo, M.-S., Chagnon, G., Verron, E., Ch'ng S.-Y. (2015).
    Modeling the Mullins effect in elastomers swollen by palm biodiesel.
    International Journal of Engineering Science, 95, 1-22. doi link and HAL

    [25] Chagnon, G., Rebouah, M., Favier, D. (2015).
    Hyperelastic energy densities for soft biological tissues: a review.
    Journal of Elasticity, 120, 129-160. doi link and HAL

    [24] Meunier, L., Chagnon G., Favier, D., Orgéas, L.,(2015).
    Anisotropic large deformation of geometrically architectured unfilled silicone membranes.
    European Journal of Mechanics - A/Solids, 50, 87-99. doi link and HAL

    [23] Rebouah, M., Chagnon, G., Favier, D. (2015).
    Development and modelling of filled silicone architectured membranes.
    Meccanica, 50, 11-24. doi link and HAL

    [22] Rey, T., Le Cam, J.-B., Chagnon, G., Favier, D., Rebouah, M., Razan, F., Robin, E., Didier, P., Heller, L., Faure, S. and Janouchova, K. (2014)
    An original architectured NiTi silicone rubber structure for biomedical applications.
    Materials Science and Engineering C, 45, 184-190. doi link and HAL

    [21] Rey, T., Chagnon, G., Favier, D., and Le Cam, J.-B. (2014)
    Hyperelasticity with rate-independent microsphere hysteresis model for rubberlike materials.
    Computational Materials Science, 90, 89-98. doi link and HAL

    [20] Rebouah, M., Chagnon, G. (2014).
    Extension of classical viscoelastic models in large deformation to anisotropy and stress softening.
    International Journal of non-linear mechanics, 61, 54-64. doi link and HAL

    [19] Rebouah, M., Chagnon, G. (2014).
    Permanent set and stress softening constitutive equation applied to rubber like materials and soft tissues.
    Acta Mechanica, 225, 1685-1698. doi link and HAL

    [18] Machado G., Chagnon G., and Favier D. (2014)
    Theory and identification of a constitutive model of induced anisotropy by the Mullins effect.
    Journal of the Mechanics and Physics of Solids, 63, 29-39 doi link and HAL

    [17] Linardon, C., Favier, D., Chagnon, G., Gruez, B. (2014).
    A conical mandrel tube drawing test designed to assess failure criteria.
    Journal of Materials Processing Technology, 214, 447-357 doi link and HAL

    [16] Rey, T., Razan, F., Robin, E., Faure, S., Le Cam, J.-B., Chagnon, G., Girard, A., and Favier, D. (2014).
    Mechanical characterization and comparison of different NiTi/silicone rubber interfaces.
    International Journal of Adhesion and Adhesives, 48, 67-74 doi link and HAL

    [15] Robert, A., Chagnon, G., Cinquin P. and Moreau-Gaudry, A. (2013).
    Using a 3D needle-tissue force distribution basis to optimise the design of an instrumented needle.
    Computer Methods in Biomechanics and Biomedical Engineering, 16, 320-322 doi link and HAL

    [14] Robert, A., Chagnon, G., Bricault I., Cinquin P. and Moreau-Gaudry, A. (2013).
    A generic three-dimensional loading basis applied to a surgical needle inserted into a complex tissue.
    Journal of the Mechanical Behavior of Biomedical Materials, 28, 156-170 doi link and HAL

    [13] Rebouah, M., Machado, G., Chagnon, G., Favier, D. (2013).
    Anisotropic Mullins stress softening of a deformed silicone holey plate.
    Mechanics Research Communications, 49(1), 36-43 doi link and HAL

    [12] Palengat, M., Chagnon, G., Favier, D., Louche, H., and Plaideau, C. (2013).
    Cold drawing of 316L stainless steel thin-walled tubes: Experiments and finite element analysis.
    International Journal of Mechanical Sciences, 70, 69-78 doi link and HAL

    [11] Rey, T., Chagnon, G., Le Cam, J.-B., and Favier, D. (2013).
    Influence of the temperature on the mechanical behavior of two silicone rubbers above crystallization temperature.
    Polymer Testing, 32, 492-501 doi link and HAL

    [10] Chagnon, G., Gaudin, V., Favier, D., Orgéas, L., and Cinquin, P. (2012).
    An osmotically inflatable seal to treat endoleaks of type 1, following endovascular aneurysm repair.
    Journal of Mechanics in Medicine and Biology, 12 doi link and HAL

    [9] Machado, G., Chagnon, G., and Favier, D. (2012).
    Induced anisotropy by the Mullins effect in filled silicone rubber.
    Mechanics of Materials, 50(1), 70-80 doi link and HAL

    [8] Machado, G., Favier, D., and Chagnon, G. (2012).
    Membrane Curvatures and Stress-strain Full Fields of Axisymmetric Bulge Tests from 3D-DIC Measurements. Theory and Validation on Virtual and Experimental results.
    Experimental Mechanics, 52(7), 865-880 doi link and HAL

    [7] Toungara, M., Chagnon, G., and Geindreau, C. (2012).
    Numerical analysis of the wall stress in abdominal aortic aneurysm: influence of the material model nearly-incompressibility.
    Journal of Mechanics in Medicine and Biology, 12 doi link and HAL

    [6] Machado, G.,Chagnon, G., and Favier D. (2010).
    Analysis of the isotropic models of the Mullins effect based on filled silicone rubber experimental results.
    Mechanics of Materials, 42(9), 841-851 doi link and HAL

    [5] Meunier, L., Chagnon G., Favier, D., Orgéas, L., and Vacher, P. (2008).
    Mechanical experimental characterisation and numerical modelling of an unfilled silicone rubber.
    Polymer Testing, 29, 765-777 doi link and HAL

    [4] Chagnon G., Verron, E., Marckmann, G. and Gornet, L. (2006).
    Development of new constitutive equations for mullins effect in rubber using the network alteration theory.
    International Journal of Solids and Structures, 43, 6817-6831 doi link and HAL

    [3] Chagnon G., Verron, E., Gornet, L., Marckmann, G. and Charrier, P. (2004).
    On the relevance of continuum damage mechanics as applied to the Mullins effect: theory, experiments and numerical implementation.
    Journal of the Mechanics and Physics of Solids, 52, 1627-1650 doi link and HAL

    [2] Chagnon G., Marckmann, G. and Verron, E. (2004).
    A comparison of the physical model of Arruda-Boyce with the empirical Hart-Smith model and the Gent model.
    Rubber Chemistry and Technology, 77, 724-735 doi link and HAL

    [1] Marckmann, G., Verron, E., Gornet, L., Chagnon G., Charrier, P. and Fort, P. (2002).
    A theory of network alteration for the Mullins effect.
    Journal of the Mechanics and Physics of Solids, 50, 2011-2028 doi link and HAL

    Patent

    [1] Favier, D., Alonso, T., Chagnon, G., Liu, Y., and Moreau-Gaudry, A. (2011)
    Aiguille médicale à trajectoire modifiable et pieu pilote à rigidités multiples réalisées par traitement thermique local.
    FR 1159387.

    Chapter in Book

    [2] Chagnon, G., Ohayon, J., Martiel, J.-L., Favier, D. (2017)
    Hyperelasticity modeling for incompressible passive biological tissues.
    in Biomechanics of Living Organs, Yohan Payan and Jacques Ohayon editors, Springer-Verlag. HAL

    [1] Luboz, V., Promayon, E., Chagnon, G., Alonso, T., Favier, D., Barthod, C. et Payan, Y. (2012)
    Validation of a Light Aspiration device for in vivo Soft Tissue Characterization (LASTIC).
    in Soft Tissue Biomechanical Modeling for Computer Assisted Surgery, Yohan Payan editor, Springer-Verlag. HAL

    Conference list

    Visit HAL

    PhD Students

    [13] Edouard Girard (2018)
    Development of a bilary resorbable prosthesis to secure bilary anastomosis in liver transplant.
    University of Grenoble Alpes.
    PhD Supervisor with Benjamin Nottelet

    [12] Estephanie Grassi (2018)
    Anisotropic behaviour of thin walled medical tubes in Nickel-Titanium superelastic shape memory alloys.
    University of Grenoble Alpes.
    PhD Supervisor with Denis Favier pdf

    [11] Masri Christopher (2017)
    Study of an occlusive cuff for a smat artificial urinary sphincter.
    University of Grenoble Alpes.
    PhD Supervisor with Denis Favier Confidential.

    [10] Schaefer Pierre-Loup (2017)
    Reconstruction de la déformée d'une aiguille instrumentée.
    University of Grenoble Alpes.
    PhD Supervisor with Philippe Cinquin and Alexandre Moreau-Gaudry pdf

    [9] Brèche Quentin (2016)
    Copolymères triblocs biodégradables PLA-b-PEG-b-PLA pour ingénierie tissulaire. Caractérisation et modélisation de l’évolution de leurs propriétés mécaniques au cours de leur dégradation par hydrolyse.
    University of Grenoble Alpes.
    PhD Supervisor with Denis Favier pdf

    [8] Alonso Thierry (2015)
    Characterization by DMA test and thermomechanical behaviour optimization of NiTi wires - Application to a medical steerable needle.
    University of Grenoble Alpes.
    PhD Supervisor with Denis Favier pdf

    [7] Rebouah Marie (2014)
    Anisotropic stress softening and viscoelasticity in rubber like materials and architectured materials
    University of Grenoble. pdf

    [6] Rey Thierry (2014)
    Contribution to the elaboration, experimentation shape memory alloy Nickel-Titanium/silicone rubber composites
    University of Grenoble.
    PhD Supervisor with Denis Favier and Jean-Benoit Le Cam pdf

    [5] Robert Adeline (2013)
    Navigation d'une aiguille médicale déformable
    University of Grenoble.
    PhD Supervisor with Philippe Cinquin and Alexandre Moreau-Gaudry pdf (in French)

    [4] Linardon Camille (2013)
    Étirage de tubes de précision pour applications biomédicales. Contribution à l'analyse et l'amélioration du procédé par expérimentation, modélisation et simulation numérique
    University of Grenoble.
    PhD Supervisor with Denis Favier pdf

    [3] Machado Guilherme (2011)
    A contribution to the study of induced anisotropy by Mullins effect in silicone rubber
    University of Grenoble.
    PhD Supervisor with Denis Favier pdf

    [2] Palengat Muriel (2009)
    Modélisation des couplages multiphysiques matériaux-produits-procédés lors de l'étirage de tubes : applications aux alliages métalliques usuels
    University of Grenoble - Collaboration Minitubes SA.
    PhD Supervisor with Denis Favier pdf (in French)

    [1] Meunier Luc (2008)
    Contribution à la conception, l’expérimentation et la modélisation de membranes hyperélastiques architecturées anisotropes
    University of Grenoble.
    PhD Supervisor with Denis Favier

    Some Projects

    ANR - RAMMO (Eel-Like Robot with electric sense) 2007-2011

    This ANR Project aiming at the design, construction and control of a 3D eel-like robot with electrical sensing that is usually used by the electric fishes. The robot is composed of 12 vertebras connected through a rotation free joints. The whole robot is covered with a skin that is especially designed in order to avoid perforation due to the water pressure while allowing an easy swimming oriented ondulations. Our team role in this project is to design this skin, composed by a special silicone rubber material.
    Leader: F. Boyer
    Partners: IRCCyN (Nantes)/ GIPSA-LAB (Grenoble) / LMF (Nantes) / SUBATECH (Nantes) / UNIC (Paris)

    Eel Robot

    ANR - ANiM (Architectured Ni-Ti Materials) 2010-2014

    This project aims to develop a new category of innovative materials combining the intrinsic and novel properties of Nickel-Titanium shape memory alloys with purposely engineered topologies allowed by the notion of “architectured materials”. More specifically, we aim to create architectured materials constituted of NiTi wires and tubes. Using fibres cut from thin wires, we will create non-woven random 2D textiles, 3D blocks of low solid densities, and more complex designed architectures. With thin-wall tubes we will create regular cellular materials. To realise these unique structures we apply a range of innovative materials processing techniques, such as plasma sintering, electric resistance welding, diffusion brazing, and silicone elastomer infiltration.
    Our team role is to study and improve the interface between NiTi and silicone rubber.
    Leader: D. Favier
    Partners: LMGC (Montpellier)/ SIMAP (Grenoble) / LARMUR (Rennes) / LIMATB (Lorient) / 3SR (Grenoble)

    NiTi ANiM

    ANR - SAMBA (Silicone Architectured Membranes for Biomedical Applications) 2012-2016

    This project takes its source in an array of works aiming at designing highly deformable anisotropic membranes for medical applications. The silicone rubbers are highly deformable biomaterials widely used by surgeons for their mechanical properties controlled by their crosslinking rate. In current medical applications, the properties of silicones are homogeneous and isotropic. In the present biomimetic approach, our researches aim to provide the clinician elastomeric membranes whose local properties can possibly be non-uniform and will be fully controlled during their elaboration, both in rigidity and anisotropy.
    Leader: G. Chagnon
    Partners: IMP (Lyon)/ MATEIS (Lyon)

    Samba Project Samba Project

    ANR - BioScaff (Hyperelastic and absorbable architected materials dedicated to soft tissue reconstruction) 2016-2020

    This multidisciplinary project is part of the development of new cell growth supports or "scaffolds" dedicated to soft tissue regeneration. In order to optimize the development of new implantable medical devices, the objective of the project is to set up and validate a methodology for predicting the evolution of the mechanical properties of biocomposite "growing scaffold / tissue tissue" during antagonistic effects. Biodegradation of scaffold and its colonization by the biological tissue. For this purpose, new bioresorbable and biocompatible block polymers with hyperelastic behaviour close to soft tissues will be synthesized. These materials will be shaped by electrospinning to produce biomimetic supports promoting cell growth. The mechanical properties of its supports will be characterized in the presence of growing cells at different stages of degradation. Numerical simulation methods, from the cell scale to the support, will integrate the experimental results obtained to characterize and ultimately predict the mechanical behaviour supports based on these intrinsic properties.
    Leader: F. Bossard
    Partners: LRP (Grenoble) / IBMM (Montpellier)

    Contact

    phone: +33 (0)4 56 52 00 86
    fax: +33 (0)4 76 76 88 44
    email: gregory [dot] chagnon [at] univ-grenoble-alpes [dot] fr

    Address:
    Laboratoire TIMC-IMAG - BioMMat Team
    Pavillon TAILLEFER
    IN3S INstitut de l'INgénierie et de l'INformation de Santé
    38706 LA TRONCHE CEDEX - FRANCE
    map with GPS coordinates